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Alpha Thalassemia Genotyping Kit -- αTHA-gapPCR

Nondeletion Alpha Thalassemia Genotyping Kit -- dαTHA-RDB

Beta Thalassemia genotyping kit -- βTHA-RDB

Beta Thalassemia Gene Assay Kit -- βTHA-MMC

Thalassemia Genotyping Kit -- THA-RDB

Deletion Alpha Thalassemia Gene Assay Kit -- dαTHA-MMC

Non-deletion Alpha Thalassemia Gene Assay Kit -- ndαTHA-MMC

Spinal Muscular Atrophy Genetic Testing Kit -- SMN1

Thalassemia Genotyping Kit -- THA-RDB

Clinical Application

Thalassemia is a genetic hemolytic disease due to the occurrence of defects in the globin gene, resulting in reduced or not synthesis of globin chain synthesis, so that the ratio of globin chain to form hemoglobin is imbalance. It mainly includes two types: Alpha –thalassemia (α-thalassemia) and Beta-thalassemia (β-thalassemia).

α-thalassemia (including deletion type α-thalassemia and non-deletion type α-thalassemia) is one of the most commonly seen single gene inheritance diseases in the world. The commonly seen deletion type α-thalassemia genetypes are -α^3.7, -α ^4.2 and --^SEA. These three different types of deletions in the individual can be expressed as quiescent, standard, hemoglobin H (HbH) and Hb Bart′s Hydrops Fetalis. The common non-deletion type α-thalassemia genotypes are α^CSα、α^QSα and α^WSα. Non-deletion type α-thalassemia is one of the leading causes of clinical missed diagnosis of α-thalassemia.

β-thalassemia is caused by β-globin gene mutation. The commonly mutation loci are CD41/42, IVS-Ⅱ-654, -28, CD71/72, etc.

Intended Use

This kit is used for the in vitro qualitative detection of human whole blood genomic DNA sample, which can detect 3 kinds of deletion type α -thalassemia gene mutation (--^SEA 、-α^3.7and -α^4.2), 3 kinds of non-deletion type α-thalassemia gene mutation (α^{Constant Spring}α(α^CSα)、α^{Quong Sze}α(α^QSα) and αWestmeadα(α^WSα) and 17 kinds of β-thalassemia gene mutation (41-42M, 654M, -28M, 71-72M, 17M, βEM, IVS-I- 1M, IVS-I-5M, 27/28M, 43M, -29M, -30M, 31M, -32M, 14- 15M, IntM and CAPM).

Packing Specifications

25 tests/kit (single test/tube)

25 tests/kit (non-single test/tube)

48 tests/lit (non-single test/tube)

General Specification

Methodology: PCR-Reverse Dot Blot
Sample Type: anti-coagulation whole blood
Precision: CV <5%
LoD: 10 ng/μL

Clinical Application

Intended Use

Packing Specifications

General Specification

Demonstration of Results